Pictured, L to R:
Brian Reilly; Tim Luger; Rafael Bejar, MD, PhD;
Tiffany Tanaka, MD; Armon Azizi
Every dollar helps our cause, but we also need additional volunteers who are willing to give us a few hours of their time on a committee for our annual fundraising event, letter writing campaign, or several other opportunities.
Hope For a Cure Foundation has a unique mission. We use almost 100% of every donated dollar to purchase equipment for local cancer researchers/physicians in San Diego. We are all volunteers, and this is our passion.
Co-Founder, volunteer, cheerleader and President extraordinaire.
We are currently accepting proposals in order to determine our next physician/scientist recipient. We appreciate your interest and support and will publish that information soon. Stay tuned!
CFO, sponsor (Liedle, Larson, Lidl & Vail), volunteer (and director of music!).
Co-Founder, volunteer, survivor, and director of media.
Share our mission with others in your circle, and together, we'll make a greater difference!
For more than a decade, Hope For a Cure Foundation has devoted its energy to passionately advocating for researchers who need extra equipment to conduct their research. Find out how you can contribute to the future of a world without cancer through donations of money and/or time.
Volunteer, survivor and advocate for research and early detection.
A LETTER FROM DR. RAFAEL BEJAR
Divisions of Hematology-Oncology & Bone Marrow Transplantation - UCSD Moores Cancer Center
January 25, 2017
Our clinical practice and research concentrates on understanding the genetic factors that drive myelodysplastic syndromes (MDS), a group of bone marrow disorders that cause low blood counts and can progress to acute myeloid leukemia.We received a generous donation from the Foundation who purchased equipment for our laboratory that has allowed us to pursue new avenues of research. The equipment included an ultrasonic liquid processing device that uses sound energy to disrupt cells, releasing their proteins and other molecules for analysis. We have used this device to examine protein levels in cells designed to study how drugs used in the treatment of MDS exert their effects. Another piece of equipment included a nano-drop spectrophotometer. This machine uses a laser to determine how pure a sample of DNA or RNA is and how concentrated it is. The nano-drop is the backbone for many of our research projects, because much of what we do in the lab involves DNA derived from MDS patient samples. Sample quantity and purity are key factors in the success of many of our experiments. The nano-drop is able to analyze DNA samples in extremely small volumes, as low as 1 micro-liter (1/1,000,000 of a liter). This is important because the DNA that we work with may have been isolated from patients many years prior. These samples are precious and irreplaceable. By allowing us to waste only a tiny fraction using the nano-drop, we preserve as much of these important samples for subsequent studies. The third hi-tech piece of equipment donated to us was a Qubit 3.0 Fluorimeter. This device is also used to quantify DNA, RNA, as well as proteins, but uses fluorescence to measure these quantities. This technique is more sensitive and accurate than the nano-drop, but requires more sample and more cost. We reserve it for the most sensitive experiments like those involving Next-Generation Sequencing to determine a patient’s genetic mutation profile, epigenetic profile, or gene-expression profile. The Qubit allows us to get the most out of each expensive sequencing run. In total, the Foundation’s donation of these pieces of equipment have expanded the capabilities of our laboratory into new and exciting areas. It has aided our work towards better care and treatments for patients with blood cancers like MDS. We are deeply grateful to the members of the Hope for a Cure Foundation for their generosity and altruism.